Resources

HSPC Classifier

We developed a machine learning classifier to annotate human hematopoietic stem and progenitor cell (HSPC) populations from bone marrow single-cell RNA-seq data. This tool can be used to annotate your scRNA-seq data based on cell types identified in our prior work.

LSC Reference

Using single-cell multi-omics, were able to identify AML LSCs at high resolution and purity. We developed an integrated single cell data set and reference signature matrix for bulk gene expression deconvolution as part of this study. The methods used to generate these tools are provided here.